How our cells sense oxygen wins Nobel prize

Three scientists who discovered how cells adapt to oxygen share the prize for physiology or medicine.
BBC News – Health
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New brain cells made throughout life

The study could lead to new ideas for treating Alzheimer’s disease, say the researchers.
BBC News – Health
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Fat-clogged cells explain why obesity can cause cancer

A type of cell the body uses to destroy cancer gets clogged by fat and stops working, findings suggest.
BBC News – Health
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DNA tweak ‘boosts’ cancer-killing cells

Cancer scientists have genetically modified the immune system to help them attack tumours in mice.
BBC News – Health
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Stem Cells Yield Lab-Grown Skin, Researchers Say

Finding might boost study of skin conditions, and eliminate testing of drugs and cosmetics on animals
healthfinder.gov Daily News
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Cell Differentiation of Neoplastic Cells Originating in the Oral and Craniofacial Regions

Cell Differentiation of Neoplastic Cells Originating in the Oral and Craniofacial Regions


Development of the oral and craniofacial region is a complex and fascinating set of processes which require a sequential integration of numerous biological steps. For medical and dental doctors, interest is particularly high in this region, because it is composed of three blastoderms – ectoderm, mesoderm and endoderm – as well as neural crest cells. There are many different types of neoplasms in this region. In general, proliferation, development and cytological differentiation of the neoplastic cells reflect the normal physiological development of the outbreak mother cells and/or tissues. Collected human neoplasm cases, such as osteosarcoma appearing in the oral and craniofacial region, are examined regarding the immunohistochemical expression of some morphogenesis regulation factors. Furthermore, examination of Notch signalling is also conducted for some odontogenic neoplasms.This book mainly describes the examination results of some morphogenesis regulation factors, such as Notch signalling, in the neoplastic cells originating in the oral and craniofacial region, especially in the odontogenic neoplasms, in both well-differentiated and poorly-differentiated neoplasms of tooth germ enamel organ-derived neoplasm.In general, these morphogenesis regulation factors are responsible for cytological regulation of cell fate, morphogenesis and/or development. The results suggest that these factors play some role in cytological differentiation or acquisition of tissue specific characteristics in neoplastic cells. Furthermore, there would appear to be a relationship between the cytological differentiation in the oral and craniofacial neoplastic cells and the physiological development and differentiation of their originating mother cells and tissues of the oral and craniofacial region.

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